Journal of Antimicrobial Chemotherapy · 1995 · 22 citations · 0 references
Life SciencesInfectious DiseasesMicrobiologyAntimicrobial ResistanceMedical MicrobiologyMicrobial PathogenesisAntibacterial ResistanceAntibiotic ResistanceAntibiotic Resistance GeneticsAntibiotic Resistance MechanismsBacterial InfectionsMechanisms Of Antimicrobial ResistanceDrug Resistance TestingGenetic Risk MarkersMolecular Drug ResistanceMolecular Drug Susceptibility TestingMycobacterium Tuberculosis InfectionPhenotypic Drug Susceptibility TestingRifampicin TherapyTuberculosis Drug Resistance
Mycobacterium avium, Mycobacterium intracellulare complex (MAC) bacilli are an important cause of bacteraemia in AIDS patients but treatment is complicated by their resistance to the usual antimycobacterial agents. In this study of 20 strains of MAC none was found to have the mutations associated with resistance to rifampicin and streptomycin in M. tuberculosis suggesting that MAC have unique mechanisms for resistance to these agents.