2,3-Diaryl-substituted indole based COX-2 inhibitors as leads for imaging tracer development

Abstract

A series of 2,3-diaryl-substituted indoles containing a fluorine or methoxy group was synthesized <italic>via</italic> Fischer indole synthesis, McMurry cyclization, or Bischler–Möhlau reaction to identify potential leads for PET radiotracer development.