The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways

Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes

Olivier Micheau, Jürg Tschopp · Cell · 2003 · 2.6K citations · Full text

Signal Transduction, Signaling Pathway, Molecular Pathway +7

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

Liming Sun, Huayi Wang, Zhigao Wang et al. · Cell · 2012 · 2.6K citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +7

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

Young-Sik Cho, Sreerupa Challa, David Moquin et al. · Cell · 2009 · 2.4K citations · Full text

Inflammation, Phosphorylation-driven Assembly, Viral Replication +9

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

Sudan He, Lai Wang, Lin Miao et al. · Cell · 2009 · 2.2K citations

Inflammation, Cytokine, Signal Transduction +11

Identification of RIP1 kinase as a specific cellular target of necrostatins

Alexei Degterev, Junichi Hitomi, Megan Germscheid et al. · Nature Chemical Biology · 2008 · 2K citations · Full text

Reductive Stress, Specific Cellular Target, Signal Transduction +13