Brush‐Like Polycarbonates Containing Dopamine, Cations, and PEG Providing a Broad‐Spectrum, Antibacterial, and Antifouling Surface via One‐Step Coating

Abstract

An antibacterial and antifouling surface is obtained by simple one-step immersion of a catheter surface with brush-like polycarbonates containing pendent adhesive dopamine, antifouling polyethylene glycol (PEG), and antibacterial cations. This coating demonstrates excellent antibacterial and antifouling activities against both Gram-positive (S. aureus) and Gram-negative (E. coli) bacteria, proteins, and platelets, good stability under simulated blood-flow conditions, and no toxicity.