Multiplex Imaging of Single Tumor Cells Using Quantum‐Dot‐Conjugated Aptamers

Abstract

Aptamers conjugated with quantum dots (QDs) bind to target molecules on the cellular membrane of cancer cells. QDs with a carboxyl terminal are conjugated with three types of tumor-targeting aptamer (see picture). Various types of cancer cell are simultaneously targeted with QD-TTA1 (605nm, light green), QD-AS1411 (655nm, red), and QD-MUC-1 (705nm, violet). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.