Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression - Concepedia

Concepedia

Publication | Open Access

Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression

DOI Full Paper Access

163

Citations

42

References

2015

Year

Xavier Loyer, Valérie Paradis, Carole Hénique, Anne-Clémence Vion, Nathalie Colnot, Coralie L. Guérin, Cécile Devue, Sissi On, Jérémy Scetbun, Mélissa Romain,

Abstract

MicroRNA-21 inhibition or suppression decreases liver injury, inflammation and fibrosis, by restoring PPARα expression. Antagomir-21 might be a future therapeutic strategy for NASH.

References

	Year	Citations

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