Journal of Heterocyclic Chemistry · 2006 · 61 citations · 15 references
Natural SciencesChemistryMedicinal ChemistryCatalysisGreen ChemistrySynthetic Medicinal ChemistryCatalyst PreparationHeterocycle SynthesisReaction PathwaysHeterocycle FunctionalizationOne-pot Heterocycle SynthesisSolvent-free Catalysis
Abstract magnified image Three component coupling of one pot reaction which servers as the most convenient route to the synthesis of benzopyran derivatives using the TiCl 4 catalyst (10 mol %) under solvent free conditions is described. The procedure offers a systematic method with a number of advantages including operational simplicity, neat reactions, reduced reaction time, high yields of products and applicability to large scale reactions.
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The natural coumarins: Occurrence, chemistry and biochemistry
David E. Games · Endeavour · 1983 · 762 citations