Journal of Psychopharmacology · 2008 · 27 citations · 37 references
MedicineBehavioral SciencesPsychologyAddiction PsychiatrySleep MedicineSubstance Use DisordersSleep AssessmentSleep DisturbanceSleep HealthSleep PhysiologySleep-related FactorsSleep-wake DisordersNight AwakeningsNighttime AwakeningsSleepSleep QualitySleep Quality AssessmentSleep TimeSubjective Sleep MeasurementSubjective Sleep Quality
This study sought to test the association between ecstasy-use and abnormal sleep. An anonymous web-based questionnaire containing questions on drug use and sleep was completed by 1035 individuals. From this large sample, a group of 89 ecstasy users were found who reported very little use of other drugs. This "ecstasy-only" group was further divided into two groups of 31 current users and 58 abstinent users. The subjective sleep of current and former ecstasy-only users was compared with that of matched controls. Patients were asked to rate their sleep according to: 1) sleep quality, 2) sleep latency, 3) night time awakenings and 4) total sleep time. Current ecstasy-only users reported significantly worse sleep quality (P < 0.05) and a greater total sleep time (P < 0.001) than controls. It was inferred that these differences might be due to recovery from the acute effects of the drug. Abstinent ecstasy-only users reported significantly more nighttime awakenings than controls (P < 0.01). These subjective findings are in agreement with the objective findings of previous studies showing persistent sleep abnormalities in ecstasy users.
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The International Journal of Neuropsychopharmacology
Bernard Lerer, Alan Frazer, Stephen M. Stahl et al. · The International Journal of Neuropsychopharmacology · 1998 · 506 citations
Medicine, Pharmacology, Psychiatry +10
Giuseppe Battaglia, S.Y. Yeh, Elizabeth O’Hearn et al. · Journal of Pharmacology and Experimental Therapeutics · 1987 · 459 citations
Medicine, Neuroscience, Pharmacology +16