Bupivacaine—the deadly friend of intervertebral disc cells?

Factors involved in the nutrition of the human lumbar intervertebral disc: cellularity and diffusion of glucose in vitro.

Alice Maroudas, R. A. Stockwell, A Nachemson et al. · PubMed · 1975 · 577 citations

Medicine, Anatomy, Nutrition +9

2009 ISSLS Prize Winner: Does Discography Cause Accelerated Progression of Degeneration Changes in the Lumbar Disc

Eugene J. Carragee, Angus S. Don, Eric L. Hurwitz et al. · Spine · 2009 · 479 citations

Medicine, Orthopaedic Surgery, Radiology +17

Comparison of Ropivacaine and Bupivacaine Toxicity in Human Articular Chondrocytes

Samantha L. Piper, Hubert T. Kim · Journal of Bone and Joint Surgery · 2008 · 265 citations

Veterinary Medicine, Orthopaedic Surgery, Surgery +14

In Vitro Exposure to 0.5% Bupivacaine Is Cytotoxic to Bovine Articular Chondrocytes

Constance R. Chu, Nicholas J. Izzo, Nicole E. Papas et al. · Arthroscopy The Journal of Arthroscopic and Related Surgery · 2006 · 252 citations

Veterinary Medicine, Toxicology, Veterinary Pharmacology +6

Chondrolysis After Continuous Intra‐Articular Bupivacaine Infusion: An Experimental Model Investigating Chondrotoxicity in the Rabbit Shoulder

Andreas H. Gomoll, Richard W. Kang, James M. Williams et al. · Arthroscopy The Journal of Arthroscopic and Related Surgery · 2006 · 235 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +12