Concepedia

Effect of recombinant activated factor VII on perioperative blood loss in patients undergoing retropubic prostatectomy: a double-blind placebo-controlled randomised trial

Philip W. Friederich, C. P. Henny, Embert J. Messelink, M. Geerdink, Tymen Keller, Karl‐Heinz Kurth, Harry R. Büller, Marcel Levi

The Lancet · 2003 · 413 citations · 24 references

Concepts

MedicinePerioperative MedicineSurgeryPerioperative Outcomes ResearchBlood Loss AssessmentBlood Loss ManagementPerioperative Blood ManagementQuantification Of Blood LossIntraoperative Blood Loss ControlIntraoperative Blood Loss ReductionOperative Blood LossPerioperative Blood Loss ManagementRecombinant Activated Factor ViiRetropubic ProstatectomyRetropubic Radical Prostatectomy

References

24

Biochemistry and Physiology of Blood Coagulation

Kenneth G. Mann · Thrombosis and Haemostasis · 1999 · 456 citations

Life Sciences, Biochemistry, Physiology +16

The Tissue Factor Pathway: How It Has Become a “Prima Ballerina”

Samuel I. Rapaport, L. Vijaya Mohan Rao · Thrombosis and Haemostasis · 1995 · 407 citations

Life Sciences, Biochemistry, Cell Biology +8

Recombinant factor VIIa corrects prothrombin time in cirrhotic patients: A preliminary study

DE Bernstein, L. Jeffers, Elisabeth Erhardtsen et al. · Gastroenterology · 1997 · 254 citations

Medicine, Hematology, Pharmacotherapy +17

A randomized, double‐blind comparison of two dosage levels of recombinant factor VIIa in the treatment of joint, muscle and mucocutaneous haemorrhages in persons with haemophilia A and B, with and without inhibitors

Lusher · Haemophilia · 1998 · 214 citations

Medicine, Pharmacology, Pharmacotherapy +14

The activation of factor X and prothrombin by recombinant factor VIIa in vivo is mediated by tissue factor.

Hugo Ten Cate, Kenneth A. Bauer, Moshe Levi et al. · Journal of Clinical Investigation · 1993 · 196 citations · Full text

Life Sciences, Biochemistry, Physiology +15