Parathyroid Hormone (PTH) and PTH-Related Peptide Domains Contributing to Activation of Different PTH Receptor–Mediated Signaling Pathways

Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium.

Abdul‐Badi Abou‐Samra, Harald Jüppner, Thomas Force et al. · Proceedings of the National Academy of Sciences · 1992 · 1K citations

Medicine, Endocrinology, Molecular Biology +17

Parathyroid Hormone Stimulates the Bone Apposition Rate Independently of Its Resorptive Action: Differential Effects of Intermittent and Continuous Administration*

Cherk S. Tam, Johan N.M. Heersche, Timothy M. Murray et al. · Endocrinology · 1982 · 615 citations

Medicine, Biochemistry, Endocrinology +14

Functional Selectivity and Biased Receptor Signaling

Terry Kenakin · Journal of Pharmacology and Experimental Therapeutics · 2010 · 492 citations

Medicine, Pharmacology, Cell Signaling +16

Distinct β-Arrestin- and G Protein-dependent Pathways for Parathyroid Hormone Receptor-stimulated ERK1/2 Activation

Diane Gesty‐Palmer, Minyong Chen, Éric Reiter et al. · Journal of Biological Chemistry · 2006 · 466 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Catabolic Effects of Continuous Human PTH (1–38) in Vivo Is Associated with Sustained Stimulation of RANKL and Inhibition of Osteoprotegerin and Gene-Associated Bone Formation

Rick L. Cain, David L. Halladay, Xuhao Yang et al. · Endocrinology · 2001 · 429 citations

Medicine, Endocrinology, Bone Metabolism +16