Concepedia

Maternal Family History of Diabetes Is Associated With a Reduced Risk of Cardiovascular Disease in Women With Type 2 Diabetes

David Bruce, Kylie Van Minnen, Wendy A. Davis, Jaspreet Mudhar, Michael Perret, Dayani P. Subawickrama, Stephanie Venkitachalam, David Ravine, Timothy M. E. Davis

Diabetes Care · 2010 · 20 citations · 20 references

DOIFull text

Open access

Abstract

A maternal family history of diabetes confers relative protection against cardiovascular disease in female patients but not in male patients with type 2 diabetes. Paternal family history is associated with risks equivalent to those without a family history of diabetes. Some of the clinical heterogeneity of type 2 diabetes is related to maternal transmission effects with differential impact on male and female patients.

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