Failure of Cloxacillin in Treatment of a Patient with Borderline Oxacillin-Resistant <i>Staphylococcus aureus</i> Endocarditis

Abstract

Clinical evidence for failure with beta-lactam therapy has been lacking for patients with borderline oxacillin-resistant Staphylococcus aureus (BORSA) infections. We describe a failure of cloxacillin for a patient with endocarditis due to BORSA. The isolate also had false-negative thermonuclease and coagulase test results.