Concepedia

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Activation of Soluble Guanylate Cyclase Reverses Experimental Pulmonary Hypertension and Vascular Remodeling

DOI

219

Citations

35

References

2006

Year

Rio Dumitrascu, Hossein Ardeschir Ghofrani, Eva Dony, Knut Beuerlein, Harald Schmidt, Johannes‐Peter Stasch, Mark Jean Gnoth, Werner Seeger, Friedrich Grimminger, Ralph T. Schermuly
Circulation

Abstract

Activation of sGC reverses hemodynamic and structural changes associated with monocrotaline- and chronic hypoxia-induced experimental pulmonary hypertension. This effect is partially dependent on endogenous nitric oxide generated by NOS3.

References

YearCitations

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