Endocrinology · 1944 · 30 citations · 0 references
Life SciencesAnimal SciencesEndocrinologyReproductive BiologyReproductive EndocrinologyReproductive PhysiologyEndocrine Regulation Of ReproductionGonadal HormonesHormonal Regulation Of ReproductionMammalian EndocrinologyPituitary Gland FunctionPituitary HormonesAge At Sexual MaturityAnterior Pituitary Hormone SecretionDelayed Sexual MaturityPituitary Gland AnatomyPituitary Gonadotroph FunctionPituitary PhysiologyPituitary-gonadal AxisThyroid Hormone Physiology
A BRIEF review of the literature reveals that the results of previous studies on the relationship between the thyroid and pituitary glands are controversial and confusing. Evans and Simpson (1930) reported that pituitary glands of thyroidectomized young female rats 5 weeks after the operation were less effective than those of normal controls in causing sexual maturity in immature rats. Hohlweg and Junkmann (1933) found that the implantation of hypophyses from thyroidectomized female rats into immature female rats did not cause estrus. Van Dyke and Chen (1935) reported that the concentration of the hormone causing ovulation was reduced in thyroidectomized rabbits. The saline suspension of the anterior hypophysis from a normal animal always caused ovulation, but not so when a similar suspension from a thyroidectomized animal was used. P'an (1940) reported that the gonadotrophic potency of the anterior pituitary gland was decreased following thyroidectomy in both rat and rabbit.