Immunoproteomics and Immunoinformatics Analysis of <i>Cryptococcus Gattii</i> : Novel Candidate Antigens for Diagnosis

Abstract

Both immunoreactive proteins and B-cell epitopes of C. gattii genotype VGII that were potentially targeted by a host humoral response were identified. Considering the evolutionary relevance of the identified proteins, we may speculate that they could be used as the initial targets for recombinant protein and peptide synthesis aimed at the development of immunodiagnostic tools for cryptococcosis.