Seroprevalence of cytotoxin‐associated gene A positive <i>Helicobacter pylori</i> strains in Changle, an area with very high prevalence of gastric cancer in South China

Abstract

Subjects in Changle had a high prevalence of H. pylori infection and a high prevalence of the CagA-positive strains. The contrast in the prevalence of CagA-positive strains, in asymptomatic subjects in two areas with differing gastric cancer mortality, supports the pathogenic role of CagA-positive strains in gastric carcinogenesis.