Concepedia

Efficacy and Safety of OnabotulinumtoxinA for Idiopathic Overactive Bladder: A Double-Blind, Placebo Controlled, Randomized, Dose Ranging Trial

Roger R. Dmochowski, Christopher R. Chapple, Victor W. Νitti, Michael B. Chancellor, Karel Everaert, Catherine Thompson, Grace Daniell, Jihao Zhou, Cornelia Haag‐Molkenteller

The Journal of Urology · 2010 · 397 citations · 19 references

DOI

Abstract

OnabotulinumtoxinA at doses of 100 U or greater demonstrated durable efficacy in the management of idiopathic overactive bladder and urinary urgency incontinence. A dose of 100 U may be the dose that appropriately balances the symptom benefits with the post-void residual urine volume related safety profile.

References

19

The standardisation of terminology of lower urinary tract function: Report from the standardisation sub‐committee of the International Continence Society

Paul Abrams, Linda Cardozo, Magnus Fall et al. · Neurourology and Urodynamics · 2002 · 8.2K citations

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The impact of overactive bladder, incontinence and other lower urinary tract symptoms on quality of life, work productivity, sexuality and emotional well‐being in men and women: results from the EPIC study

Karin S. Coyne, Christopher Sexton, Debra E. Irwin et al. · British Journal of Urology · 2008 · 811 citations

BOTULINUM-A TOXIN FOR TREATING DETRUSOR HYPERREFLEXIA IN SPINAL CORD INJURED PATIENTS: A NEW ALTERNATIVE TO ANTICHOLINERGIC DRUGS? PRELIMINARY RESULTS

Brigitte Schurch, M. Stöhrer, G. Krämer et al. · The Journal of Urology · 2000 · 790 citations

The Impact of Urinary Urgency and Frequency on Health-Related Quality of Life in Overactive Bladder: Results from a National Community Survey

Karin S. Coyne, Chris Payne, Samir Bhattacharyya et al. · Value in Health · 2004 · 348 citations · Full text

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Refractory Idiopathic Urge Urinary Incontinence and Botulinum A Injection

Linda Brubaker, Holly E. Richter, Anthony G. Visco et al. · The Journal of Urology · 2008 · 325 citations · Full text