Carbonylation of organic halides in the presence of terminal acetylenes; novel acetylenic ketone synthesis

Abstract

Aryl, heterocyclic, and vinylic halides react with carbon monoxide and terminal acetylenes at 120 °C or below and 80 atm or below in the presence of triethyl-amine and a catalytic amount of a palladium (II) complex to form acetylenic ketones in 46·7–92·9% yield.