Concepedia

Gonadotrophin-induced paracrine regulation of human oocyte maturation by BDNF and GDNF secreted by granulosa cells

Pan Zhao, Jie Qiao, Shuo Huang, Ying Zhang, Shujing Liu, L.-y. Yan, Aaron J.W. Hsueh, Enkui Duan

Human Reproduction · 2011 · 72 citations · 36 references

DOIFull text

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Abstract

These findings demonstrate that FSH and hCG treatments augment the expression of BDNF and GDNF by granulosa cells and that these granulosa-cell-derived factors are candidate paracrine factors capable of promoting oocyte maturation.

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