Fabrication of nanofibers with antimicrobial functionality used as filters: protection against bacterial contaminants

Neeta L. Lala, Ramakrishnan Ramaseshan, Bojun Li, Subramanian Sundarrajan, R.S. Barhate, Seeram Ramakrishna

Biotechnology and Bioengineering · 2007 · 264 citations · 30 references

Concepts

Abstract

A comparative study of antimicrobial activity is done using three different electrospun nanofibers namely-CA, PAN, and PVC used as control and with various amounts of AgNO(3) being treated with UV-irradiation leading to the enhancement of silver nanoparticles. DMF is used as the common solvent which helps to undergo spontaneous slow reduction at room temperature to form silver nanoparticles followed by UV-irradiation using a 400 W source. The time required for the formation of silver nanoparticles is short and they are more or less well dispersed with few such aggregates. The presence of silver nanoparticles is confirmed using various characterization techniques. The antimicrobial activity is studied using nanofibers with fabricated functionality.

References

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