Alterations in the Rat Serum Proteome during Liver Injury from Acetaminophen Exposure

Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology

Robert Tonge, Joanne Shaw, Brian Middleton et al. · PROTEOMICS · 2001 · 881 citations

Life Sciences, Molecular Biology, Biomems +8

Overview of the HUPO Plasma Proteome Project: Results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly‐available database

Gilbert S. Omenn, David J. States, Marcin Adamski et al. · PROTEOMICS · 2005 · 792 citations · Full text

Life Sciences, Biochemistry, Bioinformatics +17

The human serum proteome: Display of nearly 3700 chromatographically separated protein spots on two‐dimensional electrophoresis gels and identification of 325 distinct proteins

Rembert Pieper, Christine L. Gatlin, Anthony J. Makusky et al. · PROTEOMICS · 2003 · 517 citations

Life Sciences, Biochemistry, Molecular Biology +17

Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes

Kazuyoshi Kon, Jae‐Sung Kim, Hartmut Jaeschke et al. · Hepatology · 2004 · 494 citations · Full text

Veterinary Medicine, Cell Biology, Pharmacology +17

Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity

Zhang‐Xu Liu, Sugantha Govindarajan, Neil Kaplowitz · Gastroenterology · 2004 · 335 citations · Full text

Veterinary Medicine, Immunology, Pharmacology +16