Quantitative and Qualitative Intrapatient Comparison of ⁶⁸Ga-DOTATOC and ⁶⁸Ga-DOTATATE: Net Uptake Rate for Accurate Quantification

Abstract

(68)Ga-DOTATOC and (68)Ga-DOTATATE are suited equally well for staging and patient selection for PRRT with (177)Lu-DOTATATE. However, the slight difference in the healthy organ distribution and excretion may render (68)Ga-DOTATATE preferable. SUV did not correlate linearly with Ki and thus may not reflect the SSTR density accurately at its higher values, whereas Ki might be the outcome measure of choice for quantification of SSTR density and assessment of treatment outcome.