Wilderness and Environmental Medicine · 2010 · 274 citations · 36 references
MedicinePreventive MedicineAcute Care MedicineAcute Illness ManagementAcute Medical Illness ManagementAltitude PhysiologyMountain HazardsAltitude AdaptationAltitude Illness ManagementAltitude SafetyAltitude TestingHigh-altitude Physiology
To provide guidance to clinicians about best practices, the Wilderness Medical Society (WMS) convened an expert panel to develop evidence-based guidelines for the prevention and treatment of acute mountain sickness (AMS), high altitude cerebral edema (HACE), and high altitude pulmonary edema (HAPE). These guidelines present the main prophylactic and therapeutic modalities for each disorder and provide recommendations for their roles in disease management. Recommendations are graded based on the quality of supporting evidence and balance between the benefits and risks/burdens according to criteria put forth by the American College of Chest Physicians. The guidelines also provide suggested approaches to the prevention and management of each disorder that incorporate these recommendations.
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Prevention of High-Altitude Pulmonary Edema by Nifedipine
Peter Bärtsch, Marco Maggiorini, Manfred Ritter et al. · New England Journal of Medicine · 1991 · 441 citations · Full text
Salmeterol for the Prevention of High-Altitude Pulmonary Edema
Cláudio Sartori, Yves Allemann, Hervé Duplain et al. · New England Journal of Medicine · 2002 · 414 citations · Full text
Effect of Acetazolamide on Acute Mountain Sickness
Stanley A. Forwand, Milton Landowne, John N. Follansbee et al. · New England Journal of Medicine · 1968 · 199 citations