Increased Oxidative DNA Damage, as Assessed by Urinary 8-Hydroxy-2′-Deoxyguanosine Concentrations, and Serum Redox Status in Persons Exposed to Mercury

Abstract

Mercury exposure can induce oxidative DNA damage, whereas the antioxidative repair systems can be expected to minimize DNA lesions caused by mercury. Measurement of urinary 8-OHdG could be useful for evaluating in vivo oxidative DNA damage in mercury-exposed populations.