Antibodies to Pre‐erythrocytic <i>Plasmodium falciparum</i> Antigens and Risk of Clinical Malaria in Kenyan Children

Abstract

Kenyan children with high levels of IgG antibodies to the pre-erythrocytic antigens CSP, LSA-1, and TRAP have a lower risk of developing clinical malaria than children without high levels of these antibodies. The decreased risk of clinical malaria may be mediated in part by prevention of high-density parasitemia.