A METHOD FOR THE DETERMINATION OF TARTRATE-LABILE, PROSTATIC ACID PHOSPHATASE IN SERUM

Abstract

L(+)-Tartrate strongly inhibits prostatic acid phosphatase (Abul-Fadl and The authors suggested the application of this phenomenon and its diagnostic value as a sensitive test in elucidating doubtful or borderline cases of prostatic cancer. Based on this principle, Fishman and Lerner (1953) described a method for the determination of serum acid phosphatase of prostatic origin. This method requires larger amounts of serum, besides involving the precipitation and separation of proteins, and is more complicated and time-consuming than the method in use here.