Concepedia

Characterization of MPP+-Induced Cell Death in a Dopaminergic Neuronal Cell Line: Role of Macromolecule Synthesis, Cytosolic Calcium, Caspase, and Bcl-2-Related Proteins

Won-Seok Choi, Lorella M.T. Canzoniero, Stefano L. Sensi, Karen L. O’Malley, Byung Joo Gwag, Seonghyang Sohn, Ji‐Eun Kim, Tae Hwan Oh, Eunhee B. Lee, Young J. Oh

Experimental Neurology · 1999 · 51 citations · 39 references

DOI

Concepts

References

39

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

Zoltán N. Oltval, Curt Milliman, Stanley J. Korsmeyer · Cell · 1993 · 6K citations

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Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo.

Toshiyuki Miyashita, Stanisław Krajewski, Maryla Krajewska et al. · PubMed · 1994 · 2.2K citations

, , +13

Intracellular ATP levels determine cell death fate by apoptosis or necrosis.

Yutaka Eguchi, S Shimizu, Yoshihide Tsujimoto · PubMed · 1997 · 1.3K citations

, , +16

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation.

D P Martin, Robert E. Schmidt, PS DiStefano et al. · The Journal of Cell Biology · 1988 · 900 citations · Full text

, , +17

bcl-2 inhibits death of central neural cells induced by multiple agents.

L T Zhong, Theodore A. Sarafian, Darci J. Kane et al. · Proceedings of the National Academy of Sciences · 1993 · 628 citations

, , +17