Concepedia

A Novel Extended-Spectrum TEM-Type β-Lactamase, TEM-138, from <i>Salmonella enterica</i> Serovar Infantis

Chedly Chouchani, Renaud Berlemont, Afef Masmoudi, Moreno Galleni, Jean‐Marie Frère, Omrane Belhadj, Kamel Ben‐Mahrez

Antimicrobial Agents and Chemotherapy · 2006 · 19 citations · 17 references

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Abstract

A novel natural TEM beta-lactamase with extended-spectrum activity, TEM-138, was identified in a ceftazidime-resistant clinical isolate of Salmonella enterica serovar Infantis. Compared to TEM-1, TEM-138 contains the following mutations: E104K, N175I, and G238S. The bla(TEM-138) gene was located on a 50-kb transferable plasmid. Expression studies with Escherichia coli revealed efficient ceftazidimase and cefotaximase activities for TEM-138.

References

17

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

, , +10

Epidemiology and Successful Control of a Large Outbreak Due to <i>Klebsiella pneumoniae</i> Producing ExtendedSpectrum β-Lactamases

Carmen Peña, Miquel Pujol, Carmen Ardanuy et al. · Antimicrobial Agents and Chemotherapy · 1998 · 315 citations · Full text

, , +15

Molecular structures of penicillin-binding proteins and β-lactamases

Jean‐Marie Ghuysen · Trends in Microbiology · 1994 · 184 citations · Full text

, , +14

Development of "oligotyping" for characterization and molecular epidemiology of TEM beta-lactamases in members of the family Enterobacteriaceae

Claude Mabilat, Patrice Courvalin · Antimicrobial Agents and Chemotherapy · 1990 · 162 citations · Full text

, , +17

A complex mutant of TEM-1 beta-lactamase with mutations encountered in both IRT-4 and extended-spectrum TEM-15, produced by an Escherichia coli clinical isolate

D. Sirot, C. Recule, El Bachir Chaibi et al. · Antimicrobial Agents and Chemotherapy · 1997 · 111 citations · Full text

, , +16