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Some approaches to the synthesis of kainic acid
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1984
Year
Medicinal ChemistryEngineeringHeterocyclicAzomethine YlidesNatural SciencesOrganic ChemistryAnthelmintic Kainic AcidChemistrySynthesis MethodChemical IntermediateNatural Product SynthesisSynthetic ChemistryBiomolecular EngineeringKainic Acid
A strategy for the synthesis of the anthelmintic kainic acid is described, involving an investigation of the [3 + 2] cycloaddition reactions of some azomethine ylides obtained from the thermal ring opening of aziridines and 4,5-dihydro-1,2,3-triazoles, with cyclopentenone.