BLADDER Aδ AFFERENT NERVE ACTIVITY IN NORMAL CATS AND CATS WITH FELINE INTERSTITIAL CYSTITIS

Abstract

These data suggest that 1) bladder Adelta afferents in FIC cats are more sensitive to pressure changes than are afferents in normal cats and 2) the inhibition of afferent firing by high concentrations of KCl in FIC cats is likely the result of afferent nerve depolarization and it is consistent with the idea of increased permeability of bladder epithelium in FIC.