Neuroprotective action of group I metabotropic glutamate receptor agonists against oxygen–glucose deprivation-induced neuronal death

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

Yael Gavrieli, Yoav Sherman, Shmuel A. Ben‐Sasson · The Journal of Cell Biology · 1992 · 9.5K citations · Full text

Dna Damage, Apoptosis, Dna Analysis +16

Blockade of glutamate receptors unmasks neuronal apoptosis after oxygen-glucose deprivation in vitro

Byoung Joo Gwag, Doug Lobner, Jae‐Young Koh et al. · Neuroscience · 1995 · 256 citations

Neurophysiology, Medicine, Physiology +15

Down-regulation of protein kinase C protects cerebellar granule neurons in primary culture from glutamate-induced neuronal death.

Marco Favaron, Hari Manev, Robert Siman et al. · Proceedings of the National Academy of Sciences · 1990 · 181 citations · Full text

Apoptosis, Cell Death, Glutamate Withdrawal +22

Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures.

Jae‐Young Koh, Elizabeth E. Palmer, CW Cotman · Proceedings of the National Academy of Sciences · 1991 · 161 citations · Full text

Cortical Cultures, Excitatory Amino, Neurotransmitter +16

Caspase Inhibition Selectively Reduces the Apoptotic Component of Oxygen-Glucose Deprivation-Induced Cortical Neuronal Cell Death

Frank Gottron, Howard S. Ying, Dennis W. Choi · Molecular and Cellular Neuroscience · 1997 · 153 citations

Apoptotic Component, Neurophysiology, Apoptosis +11