Organic–Inorganic Hybrid Materials for Enantioselective Organocatalysis

Abstract

State of clay: Chiral organic–inorganic hybrid materials based on amino acid-exchanged clays are prepared and used for heterogeneous asymmetric organocatalysis. Co-inclusion of ammonium cations within interlayers greatly enhances yields and selectivities. Recyclability of the material is evaluated, showing no decrease in enantioselectivity or conversion after ten cycles.