Publication | Closed Access
Enantioselective Synthesis of (<i>R</i>)‐2‐Methylalkanoic Acids: A Convenient Approach to α‐Substituted Chiral Carboxylic Acid Derivatives
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References
2004
Year
DerivativesEngineeringBiochemistryConvenient ApproachNatural SciencesOrganic ChemistryLithium HydroperoxideHigh YieldAbstract Racemization‐free DeacylationChemistryAsymmetric CatalysisSynthetic ChemistryEnantioselective SynthesisBiomolecular Engineering
Abstract Racemization‐free deacylation of N‐acylimidazolidine‐2‐ones using lithium hydroperoxide affords the corresponding α‐substituted chiral carboxylic acids in high yield while permitting recovery of the chiral auxiliary.
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