Visual Attention Circuitry in Schizophrenia Investigated With Oddball Event-Related Functional Magnetic Resonance Imaging

Abstract

Abnormal activation in schizophrenia in response to attentional demands reflects both insufficient recruitment of brain systems required for target detection and overcommitment of resources for processing irrelevant distractors. Schizophrenia patients appear to have an inability both to focus on targets and ignore distraction.