Publication | Open Access
Helicobacter pyloriPossesses Four Coiled-Coil-Rich Proteins That Form Extended Filamentous Structures and Control Cell Shape and Motility
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Citations
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References
2011
Year
Protein AssemblyBiochemistryCoiled-coil-rich ProteinsNatural SciencesCcrp ProteinsBacteriologyVirulence FactorMolecular BiologyControl Cell ShapeMolecular GeneticsIndividual Ccrp FilamentsMicrobiologyMolecular MicrobiologyCcrp MutantsMedicineMulti-protein AssemblyStructural BiologyMicrobial Genetics
We identified two additional genes of Helicobacter pylori encoding Ccrp proteins. All four Ccrps have different multimerization and filamentation properties and different types of smallest subunits and do not copurify, suggesting a system of individual Ccrp filaments. Despite the presence of morphologically unaltered flagella, all ccrp mutants displayed significantly reduced motility.
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