A radioprotective effect of vitamin C observed in Chinese hamster ovary cells

Abstract

Vitamin C at high concentrations was found to inhibit the growth of CHO clone A cells in culture. It had a radioprotective effect, giving a maximum increase in cell survival of a factor of seven under the experimental conditions used. The protective effect was mainly but not exclusively attributable to an increase in the D0, the maximum increase observed being the order of 1.4.