Anticancer metallodrugs of glutamic acid sulphonamides: in silico, DNA binding, hemolysis and anticancer studies

Abstract

In response to an increased demand for effective anticancer drugs, a series of disodium sulphonamides of<sc>l</sc>-glutamic acid (<bold>L1–L3</bold>) was synthesized. Sulphonamides were complexed with copper(<sc>ii</sc>), nickel(<sc>ii</sc>) and ruthenium(<sc>iii</sc>) ions, separately and respectively.