Effect of heart transplantation on skeletal muscle metabolic enzyme reserve and fiber type in end‐stage heart failure patients

Abstract

Skeletal muscle glycolytic, oxidative, and beta-oxidative enzymatic reserves are diminished early after heart transplantation, with reduced oxidative capacity persisting late in the first year. The myopathic MHC phenotype present in end-stage HF persists early in the post-operative state and declines further by eight months.