Kinetics of the Absorption, Distribution, Metabolism, and Excretion of Lobeglitazone, a Novel Activator of Peroxisome Proliferator-Activated Receptor Gamma in Rats

MDCK (Madin-Darby Canine Kidney) Cells: A Tool for Membrane Permeability Screening

Jennifer D. Irvine, Lori H. Takahashi, Karen Lockhart et al. · Journal of Pharmaceutical Sciences · 1999 · 976 citations

Life Sciences, Biochemistry, Cell Biology +13

The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data

R. Scott Obach, James G. Baxter, Theodore E. Liston et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 591 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

In Vitro P-glycoprotein Assays to Predict the in Vivo Interactions of P-glycoprotein with Drugs in the Central Nervous System

Bo Feng, Jessica B. Mills, Ralph E. Davidson et al. · Drug Metabolism and Disposition · 2007 · 442 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

A comparative study of artificial membrane permeability assay for high throughput profiling of drug absorption potential

Chengyue Zhu, Lan Jiang, Teng‐Man Chen et al. · European Journal of Medicinal Chemistry · 2002 · 349 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Combined Application of Parallel Artificial Membrane Permeability Assay and Caco-2 Permeability Assays in Drug Discovery

Edward H. Kerns, Li Di, Susan Petusky et al. · Journal of Pharmaceutical Sciences · 2004 · 270 citations

Natural Sciences, Biophysics, Pharmacology +15