Politamide, a new constituent from the stem bark of Ficus polita Vahl (Moraceae)

Abstract

A new cerebroside 1 characterized as (2R,9Z)-2-hydroxy-N-{(1S,2S,3R,4S)-1-[(-Dglucopyranosyloxy)methyl]-2,3,4-trihydroxyoctacosan-1-yl}-9-pentadecenamide was isolated from the stem bark of Ficus polita Vahl (Moraceae) together with four known compounds identified as sitosterol 3-O--D-glucopyranoside 2, betulinic acid 3, stigmasterol 4 and lupeol 5. Their structures were determined on the basis of spectroscopic methods as well as HR-ESI-MS, NMR analyses, chemical transformation, and by comparison of their physical and spectral data with those reported in the literature and with authentic specimens for some known compounds.