European Journal of Organic Chemistry · 2014 · 29 citations · 83 references
EngineeringFacile AccessBiochemistryNatural SciencesDiversity-oriented SynthesisOxidative MethodCatalytic SynthesisOrganic ChemistryCatalysisChemistryN ‐Monosubstituted α‐KetoamidesOxidation ReactionSynthetic ChemistryBiomolecular Engineering
Abstract An efficient iodine‐mediated oxidation reaction for ynamides has been developed to produce N ‐monosubstituted α‐ketoamides and α‐ketoimides. This oxidative method, which exhibits good functional group tolerance, was performed under mild conditions without a metal catalyst.
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Synthetic Use of Molecular Iodine for Organic Synthesis
Hideo Togo, Shinpei Iida · Synlett · 2006 · 409 citations