Iodine‐Mediated Oxidation of Ynamides: A Facile Access to <i>N</i>‐Monosubstituted α‐Ketoamides and α‐Ketoimides

Hai Huang, Guangke He, Xiaolin Zhu, Xiaodong Jin, Shineng Qiu, Hongjun Zhu

European Journal of Organic Chemistry · 2014 · 29 citations · 83 references

Concepts

Abstract

Abstract An efficient iodine‐mediated oxidation reaction for ynamides has been developed to produce N ‐monosubstituted α‐ketoamides and α‐ketoimides. This oxidative method, which exhibits good functional group tolerance, was performed under mild conditions without a metal catalyst.

References

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