Contribution of fluorescence in situ hybridization to immunohistochemistry for the evaluation of HER-2 in breast cancer

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.7K citations

Medicine, Genetics, Oncology +14

Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment.

Mark D. Pegram, A. Lipton, Daniel F. Hayes et al. · Journal of Clinical Oncology · 1998 · 1.1K citations

Medicine, Oncology, Pharmacology +17

Assessment of Methods for Tissue-Based Detection of the HER-2/neu Alteration in Human Breast Cancer: A Direct Comparison of Fluorescence In Situ Hybridization and Immunohistochemistry

Giovanni M. Pauletti, Suganda Dandekar, Hong-Mei Rong et al. · Journal of Clinical Oncology · 2000 · 685 citations

Medicine, Cancer Biology, Oncology +17

ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization.

Olli Kallioniemi, Anne Kallioniemi, Wayne Kurisu et al. · Proceedings of the National Academy of Sciences · 1992 · 560 citations

Medicine, Genetics, Oncology +15

Detection and quantitation of HER-2/neu gene amplification in human breast cancer archival material using fluorescence in situ hybridization.

Giovanni M. Pauletti, William Godolphin, M F Press et al. · PubMed · 1996 · 560 citations

Medicine, Molecular Biology, Oncology +15