Molecules of Various Pharmacologically-Relevant Sizes Can Cross the Ultrasound-Induced Blood-Brain Barrier Opening in vivo

Noninvasive MR Imaging–guided Focal Opening of the Blood-Brain Barrier in Rabbits

Kullervo Hynynen, Nathan McDannold, Natalia Vykhodtseva et al. · Radiology · 2001 · 1.5K citations

Medicine, Biomedical Engineering, Radiology +17

Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood–brain barrier disruption

Manabu Kinoshita, Nathan McDannold, Ferenc A. Jólesz et al. · Proceedings of the National Academy of Sciences · 2006 · 649 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

<i>In vivo</i> diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space

Robert G. Thorne, Charles Nicholson · Proceedings of the National Academy of Sciences · 2006 · 636 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI‐guided focused ultrasound

Lisa H. Treat, Nathan McDannold, Natalia Vykhodtseva et al. · International Journal of Cancer · 2007 · 548 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Effect of Focused Ultrasound Applied With an Ultrasound Contrast Agent on the Tight Junctional Integrity of the Brain Microvascular Endothelium

Nickolai Sheikov, Nathan McDannold, Shipra Sharma et al. · Ultrasound in Medicine & Biology · 2008 · 495 citations · Full text

Veterinary Medicine, Bioengineering, Neuroscience +17