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Annexin A8 Is Up-Regulated During Mouse Mammary Gland Involution and Predicts Poor Survival in Breast Cancer

Torsten Stein, Karen N. Price, Joanna S. Morris, Victoria J. Heath, Roderick K. Ferrier, Alexandra Bell, Marie Anne Pringle, René Villadsen, Ole W. Petersen, Guido Sauter,

Clinical Cancer Research · 2005 · 58 citations · 36 references

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Abstract

Annexin A8 is involved in mouse mammary gland involution. In humans, it is a luminally expressed protein with basal expression in cell culture and in hyperplasia/ductal carcinoma in situ. Expression in invasive breast carcinomas has a significant effect on survival (P = 0.03) but is not independent of grade or CK5.

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