INSULA AND ANTERIOR CINGULATE GABA LEVELS IN POSTTRAUMATIC STRESS DISORDER: PRELIMINARY FINDINGS USING MAGNETIC RESONANCE SPECTROSCOPY

Abstract

PTSD is associated with reduced GABA in the right anterior insula. This preliminary evidence of the (1) H-MRS GABA metabolite as a possible biomarker of PTSD encourages replication in larger samples and examination of relations with symptom dimensions. Future studies also should examine whether insula GABA is a marker of anxiety proneness, cutting across clinical diagnostic categories.