Beilstein Journal of Organic Chemistry · 2013 · 13 citations · 12 references
PharmacyMedicinal ChemistryMicrobiologyDrug DesignDrug DiscoveryMycologyAntifungal AgentsAntifungal PharmacologyNatural Product Drug DiscoveryBiological Evaluation ReportFungal Drug DiscoveryNatural Antifungal CompoundsNew Antifungal AgentsStructural Framework Analysis
The myxobacterial strain Stigmatella aurantiaca MYX-030 was selected as promising source for the discovery of new biologically active natural products by our screening methodology. The isolation, structure elucidation and initial biological evaluation of the myxocoumarins derived from this strain are described in this work. These compounds comprise an unusual structural framework and exhibit remarkable antifungal properties.
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Klaus Gerth, Herbert Irschik, Hans Reichenbach et al. · The Journal of Antibiotics · 1980 · 188 citations · Full text