Epidemiology and Infection · 2014 · 49 citations · 18 references
VaccinationVaccine SafetyInfectious Disease EpidemiologyMaternal ImmunizationPreventive MedicineHealth CommunicationSouth WalesUk News ProgrammesDisease OutbreakDisease SurveillanceVaccine EfficacyInfection ControlPublic HealthLarge MeaslesMedicineVaccine HesitancyEpidemiologyGeneral Epidemiology
A large measles outbreak occurred in South Wales in 2012/2013. The outbreak has been attributed to low take-up of measles-mumps-rubella (MMR) immunization in the early 2000s. To understand better the factors that led to this outbreak we present the findings of a case-control study carried out in the outbreak area in 2001 to investigate parents' decision on whether to accept MMR. Parents who decided not to take-up MMR at the time were more likely to be older and better educated, more likely to report being influenced by newspapers [adjusted odds ratio (aOR) 3·07, 95% confidence interval (CI) 1·62-5·80], television (aOR 3·30, 95% CI 1·70-6·43), the internet (aOR 7·23, 3·26-16·06) and vaccine pressure groups (aOR 5·20, 95% CI 2·22-12·16), and less likely to be influenced by a health visitor (aOR 0·30, 95% CI 0·16-0·57). In this area of Wales, daily English-language regional newspapers, UK news programmes and the internet appeared to have a powerful negative influence. We consider the relevance of these findings to the epidemiology of the outbreak and the subsequent public health response.
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Infectious Diseases of Humans: Dynamics and Control
Annals of Internal Medicine · 1992 · 8K citations
Julie Leask · Nature · 2011 · 212 citations · Full text