Concepedia

A General Palladium‐Catalyzed Suzuki–Miyaura Coupling of Aryl Mesylates

Chau Ming So, Chak Po Lau, Fuk Yee Kwong

Angewandte Chemie International Edition · 2008 · 182 citations · 42 references

DOI

Concepts

Abstract

Catalyze this! The first palladium-catalyzed Suzuki–Miyaura coupling of unactivated aryl mesylates is reported, with not only arylboronic acids, but also other organoboron nucleophiles (see picture; Z=B(OH)2, BF3K, BPin). The reaction conditions are compatible with various common functional groups (R1=alkyl, OMe, CHO, CO, CN, CO2R′, heteroaryl).

References

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