Concepedia

Tranilast attenuates the up-regulation of thioredoxin-interacting protein and oxidative stress in an experimental model of diabetic nephropathy

Sih Min Tan, Y. Zhang, Alvin J. Cox, Darren J. Kelly, Weiwei Qi

Nephrology Dialysis Transplantation · 2010 · 47 citations · 48 references

DOI

Abstract

This is the first study to demonstrate that tranilast not only has anti-inflammatory and anti-fibrotic effects as previously reported but also attenuates the up-regulation of Txnip and oxidative stress in diabetic nephropathy.

References

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